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ICE COLD-PCR

ICE COLD-PCR ? Better Sensitivity and Accuracy for Mutation Detection

 

Our ICE COLD-PCR (Ice Cold PCR) technology preferentially enriches mutant DNA sequences in an excess of wild-type DNA through selective amplification of the mutant DNA. The result is up to a 500-fold increase in sensitivity in identifying mutations with the most precise sequence alteration detection rates available—down to .1% enabling mutation detection testing liquid biopsies. This capability removes the restriction for obtaining a tissue biopsy for genetic testing allowing for a more accurate diagnosis and monitoring of patients currently on therapies.

 

Ice Cold PCR Detects Mutations Accurately and Simply to Improve Patient Outcomes

 

 

The Ice Cold PCR Solution

Enable clinically relevant known and unknown mutations rapidly without major costs or impact

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More sensitive,

accurate diagnostics

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Sample source independent testing

Enables personalized treatment

Easily implemented into any laboratory

Enables more accurate diagnosis and patient outcomes

Platform Independent

 

Sanger, NGS, BEAMing,

COBAS, HRM, DHPLC,

Digital PCR and Pyro

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