Muliplexed ICE COLD-PCR (Improved and Complete Enrichment CO-amplification at Lower Denaturation temperature) technology preferentially enriches mutant DNA sequences in an excess of wild-type DNA through selective amplification of the mutant DNA. The result is up to a 500-fold increase in sensitivity in identifying mutations with the most precise sequence alteration detection rates available-down to 0.1%*.
More sensitive,accurate diagnostics
Sample source independent testing
Enables personalized treatment
Easily implemented into any laboratory
Enables more accurate diagnosis and patient outcomes
Platform Independent
Sanger, NGS, BEAMing, COBAS, HRM, DHPLC, Digital PCR and Pyro
E-mail BD@precipiodx.com for more information
Jörg Tost (2015): The clinical potential of Enhanced-ice-COLD-PCR, Expert Review of Molecular Diagnostics,
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